What is Decapeptide-12?
Decapeptide-12 is a skin-lightening peptide used in cosmetics to reduce melanin production and even skin tone. It inhibits tyrosinase, the enzyme responsible for melanin synthesis, providing brightening effects without the side effects of hydroquinone.
Mechanism
Tyrosinase Inhibition
Works by:
- Inhibiting tyrosinase enzyme
- Reducing melanin synthesis
- Lightening existing pigmentation
- Evening skin tone
Cosmetic Applications
- Hyperpigmentation treatment
- Dark spot reduction
- Skin brightening
- Melasma support
- Post-inflammatory pigmentation
Comparison with Other Lightening Agents
| Agent | Mechanism | Concerns |
|---|---|---|
| Decapeptide-12 | Tyrosinase inhibition | Minimal |
| Hydroquinone | Melanocyte toxicity | Long-term safety |
| Arbutin | Tyrosinase inhibition | Slow acting |
Summary
Key Points:
- Classification: Cosmetic skin-lightening peptide
- Mechanism: Tyrosinase inhibition
- Use: Hyperpigmentation, brightening
- Safety: Well-tolerated topical