Cortagen is a tetrapeptide bioregulator developed by Professor Vladimir Khavinson, targeting the cerebral cortex and neural tissue.
Structure
Amino Acid Sequence: Ala-Glu-Asp-Pro
One of the shortest bioactive peptides with demonstrated biological activity.
Khavinson Peptide Bioregulators
Part of Professor Khavinson's 40+ year research program producing organ-specific peptide bioregulators:
- Cortagen: Cerebral cortex
- Pinealon: Pineal gland
- Thymalin/Thymogen: Thymus
- Epitalon: Pineal/telomeres
- Cardiogen: Heart
- Vesugen: Blood vessels
Mechanism of Action
Influences gene expression for:
- Neuroprotection (anti-apoptotic pathways)
- Neurotrophic signaling (BDNF, NGF)
- Synaptic connectivity
- Antioxidant defense
Research Applications
Neuroprotection
Protective effects in models of hypoxia, ischemia, and neurotoxic injury.
Neural Regeneration
- Accelerates neural functional recovery post-injury
- Activates gene programs for neural plasticity
- Promotes axonal regeneration
- Supports myelin formation
Status
Research compound only. Not FDA approved. Available in Russia and through research suppliers.